Association of Cerebral Oxygenation During Prehospital Anaesthesia and Functional Outcome: A Prospective, Observational Multi-Centre Cohort Study of 1014 Patients.

ABSTRACT:

Background

Many patients undergoing prehospital anaesthesia may be at risk of inadequate cerebral oxygenation due to underlying conditions or adverse events like hypotension or hypoxia. This study examined whether a decrease in regional cerebral oxygen saturation (rSO₂) measured with near-infrared spectroscopy (NIRS) during prehospital anaesthesia associates with worse outcomes.

Methods

We conducted a prospective, observational study including adult patients anaesthetised by six prehospital critical care teams. A relative cerebral desaturation event (rCDE) was defined as a ≥ 10% decrease in rSO₂ for ≥ 5 min from baseline. An absolute cerebral desaturation event (aCDE) was defined as rSO₂ < 60% during anaesthesia or lower than baseline if alre

SUBMITTER: Saviluoto A 

PROVIDER: S-EPMC12685386 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature