Adjuvant Therapy and Prognosticators of Survival in Head and Neck Mucosal Melanoma.

ABSTRACT:

Objectives/hypothesis

To identify prognosticators and determine the efficacies of surgery with adjuvant radiotherapy (SR) and surgery with immunotherapy (SI) of head and neck mucosal melanoma (HNMM).

Study design

Retrospective database study.

Methods

The 2004 to 2017 National Cancer Database was queried for HNMM patients. Cox proportional hazards and Kaplan-Meier analyses evaluated prognosticators of mortality and survival benefits conferred by SR, SI, or surgery with adjuvant radiotherapy and immunotherapy (SRI). Logistic regression identified predictors of adjuvant radiotherapy or immunotherapy use.

Results

Overall, 1,910 cases (845 surgery, 802 SR, 51 SI, 101 SRI) were analyzed, with 50.3% females and an average age of 68.6 ± 13.8 years. SI was associated wi

SUBMITTER: Abiri A 

PROVIDER: S-EPMC12685567 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature