Stimulating EPA Biosynthesis in <i>Microchloropsis salina</i> through Cultivation with Selected Myxobacterial Culture Supernatants.

ABSTRACT: Microalgae have emerged as a promising and sustainable platform for the production of omega-3 polyunsaturated fatty acids, offering an alternative to fish-derived sources. Among these, Microchloropsis salina (formerly Nannochloropsis salina) is particularly attractive as a candidate due to its naturally high eicosapentaenoic acid (EPA) content. In this study, bacterial supernatants from various myxobacterial strains were evaluated for their ability to enhance microalgal growth and EPA production. Remarkably, the supernatant derived from Nannocystis sp. KYC 2844 significantly improved biomass accumulation when added at 20% (v/v) to f/2 medium, increasing dry cell weight from 1.69 g/l (control) to 2.13 g/l. Although total lipid content decreased from 25.1% to 13.0%, the

SUBMITTER: Jeon S 

PROVIDER: S-EPMC12685597 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature