Effect of general anesthesia vs. local anesthesia and collateral status on outcomes in anterior circulation occlusion.

ABSTRACT:

Background and objectives

The impact of anesthesia type on outcomes following endovascular thrombectomy (EVT) remains controversial. Collateral status assessed through perfusion imaging may provide critical insights for optimizing anesthesia strategies during EVT.

Methods

In this retrospective cohort study, functional outcomes after EVT (measured by the modified Rankin Scale score) were compared between general anesthesia (GA) vs. local anesthesia (LA) using a propensity score-matched model. The association between the hypoperfusion intensity ratio (HIR, defined as Tmax > 10s/Tmax > 6 s) and outcomes was evaluated through weighted multivariate logistic regression, with potential non-linearity explored using restricted cubic spline (RCS) regression. To validate the findings,

SUBMITTER: Chen G 

PROVIDER: S-EPMC12685674 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature