Prepectoral breast reconstruction with and without acellular dermal matrix: a systematic review and meta-analysis.

ABSTRACT:

Background

The use of acellular dermal matrix (ADM) in prepectoral implant-based breast reconstruction has become increasingly widespread, aiming to enhance prosthetic support, reduce capsular contracture, and improve aesthetic outcomes. However, ADM remains a subject of debate due to its elevated cost and concerns regarding surgical morbidity. Current evidence is largely derived from retrospective, non-randomized studies, which limits the overall strength of available data. This study aims to clarify its clinical utility by conducting a meta-analysis of postoperative complications and a systematic review.

Methods

A systematic review was conducted according to PRISMA guidelines, including observational studies comparing outcomes of prepectoral reconstruction with and without

SUBMITTER: Carrillo-Gamboa AA 

PROVIDER: S-EPMC12685784 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature