Hemithyroidectomy versus total thyroidectomy for patients with differentiated thyroid cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

The 2015 American Thyroid Association (ATA) guidelines recommended hemithyroidectomy as an acceptable treatment for patients with differentiated thyroid cancer (DTC) tumors 1-4 cm. The primary objectives of this study were to trace the accumulation of evidence supporting hemithyroidectomy prior to the release of the 2015 ATA guidelines and to synthesize the available data on surgical outcomes for hemithyroidectomy and total thyroidectomy.

Methods

PubMed was systematically searched for studies comparing hemithyroidectomy and total thyroidectomy among adult patients with DTC ≥1 cm, focusing on patient outcomes including recurrence rates, overall survival (OS), disease-free survival (DFS), and disease-specific survival (DSS). Fixed-effects or random-effects models we

SUBMITTER: Hao Q 

PROVIDER: S-EPMC12685788 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature