Cost-effective affinity support for the rapid separation of bacteria from complex food matrices.

ABSTRACT: Advancements in molecular biology have facilitated the ability to detect microbes of interest in low abundance within complex samples. Although these technologies are extremely powerful, they typically accommodate only very small volumes of liquid samples as inputs; making sample volume a critical constraint for many molecular methodologies. Because testing volumes are often restricted to the microliter range, methods that concentrate target microbes can broaden the applicability of these detection devices. Immunomagnetic separation (IMS) is an example of a sample preparation method capable of selectively concentrating targets; utilizing magnetically-sensitive materials coated with biorecognition elements to isolate targets of interest. While the commercial availability of micron-sized, co

SUBMITTER: Armstrong CM 

PROVIDER: S-EPMC12685795 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature