Effect of preoperative intranasal dexmedetomidine versus placebo on intraoperative shivering in parturients undergoing cesarean section: a randomized controlled trial.

ABSTRACT:

Background

Shivering during cesarean section under epidural anesthesia is common and may negatively affect maternal comfort, surgical conditions, and physiological stability. This single-blinded, randomized controlled trial evaluated whether preoperative intranasal dexmedetomidine reduces the incidence of shivering in parturients undergoing cesarean delivery.

Methods

A total of 170 parturients scheduled for elective cesarean section under continuous epidural anesthesia were randomized into a dexmedetomidine group (group DEX) or control group (group CON). The group DEX received 1 μg/kg intranasal dexmedetomidine (diluted to 1 mL), and the group CON received 1 mL intranasal normal saline approximately 30 min before anesthesia. The primary outcomes were the incidence, severity,

SUBMITTER: Xu G 

PROVIDER: S-EPMC12685831 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature