Associations of novel blood-derived markers of inflammation with blood pressure, arterial stiffness and heart rate in young adults.

ABSTRACT:

Background

Although C-reactive protein (CRP) is often used to assess inflammation and can predict high blood pressure (BP) and arterial stiffness, novel measures of inflammation derived from platelets, white blood cell counts, and high-density lipoprotein cholesterol (HDL-C) may also indicate possible hypertension and arterial stiffening.

Methods

We assessed the association between CRP and novel inflammatory markers and clinical BP, arterial stiffness, and heart rate (HR) in Gen2 Raine Study participants in Western Australia aged 17-22 years. Arterial stiffness was assessed using pulse-wave velocity (PWV), augmentation index (AIx), and pulse pressure (PP). Inflammatory markers included high-sensitivity CRP (hsCRP); hsCRP-to-albumin ratio; lymphocyte, monocyte, neutrophil, an

SUBMITTER: Woodman RJ 

PROVIDER: S-EPMC12685874 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature