Long-term effects of dietary protein and carbohydrate quality on prediabetes remission: results from the PREVIEW randomised multinational diabetes prevention trial.

ABSTRACT:

Aims/hypothesis

Recent studies advocate prediabetes remission as a goal in diabetes prevention, but the optimal dietary composition for prediabetes remission over the long term is unknown. We aimed to examine the long-term effects on prediabetes remission of a prudent diet with moderate protein and a moderate glycaemic index (GI) (akin to general dietary guidelines) vs a high-protein, low-GI diet.

Methods

This study is a secondary analysis of PREVIEW, which is a 3 year, multicentre, parallel, randomised trial. Adults with overweight/obesity (BMI ≥ 25 and <30 kg/m² or BMI ≥ 30 kg/m², respectively) and prediabetes (fasting glucose 5.6-6.9 mmol/l and/or 2 h glucose 7.8-11.0 mmol/l determined using an OGTT) were recruited. Eligible participants underwent an

SUBMITTER: Zhu R 

PROVIDER: S-EPMC12686045 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature