Comparison of different equations for estimating the glomerular filtration rate in pediatric kidney transplant recipients.

ABSTRACT:

Background

Accurate glomerular filtration rate estimation (eGFR) is essential for managing pediatric kidney transplant recipients. Given the physiology of pediatric patients receiving adult-donor kidneys, identifying the most appropriate plasma creatinine (PCr)-based formula-pediatric or adult-specific-is crucial.

Methods

This cross-sectional study included pediatric kidney transplant recipients (age 1-18 years) who received adult-donor kidneys. We compared agreement thresholds of various pediatric and adult PCr-based GFR equations with CKiD 2012 combined PCr‒cystatin C (PCr-CystC) equation via intraclass correlation coefficients (ICCs), concordance correlation coefficients (CCCs), total deviation index (TDI), P30 performance metric (P30), Bland-Altman plots, and receiver-op

SUBMITTER: Sukboonthong P 

PROVIDER: S-EPMC12686102 | biostudies-literature | 2026 Dec

REPOSITORIES: biostudies-literature