Circulating tumor cells as a recurrence risk marker in glioma: a retrospective study.

ABSTRACT:

Background

Glioma is a highly aggressive brain tumor with a poor prognosis due to its infiltrative nature and frequent recurrence. Current treatments often fail to achieve long-term remission, partly because of the lack of effective biomarkers for early detection and recurrence prediction. Circulating tumor cells (CTCs) have emerged as potential biomarkers in various cancers, but research on CTC detection in glioma is relatively limited, and its clinical application remains in the exploratory phase. This study aimed to characterize peripheral blood CTC as a biological biomarker for recurrence risk in glioma, laying the groundwork for prospective validation.

Methods

CTCs were isolated, identified, and quantified using the CanPatrol technique in 27 patients with glioma and 10

SUBMITTER: Huang X 

PROVIDER: S-EPMC12686197 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature