Monolithic integration of Knudsen pumps to form a complete, self-sufficient fluidic system for microscale gas chromatography.

ABSTRACT: This paper reports the first microscale gas chromatography (μGC) system in which all fluidic components are monolithically integrated into a single 15 × 15 mm² chip, including three Knudsen pumps, a preconcentrator, a separation column, and a capacitive detector. Knudsen pumps utilize thermal transpiration along narrow channels to induce gas flow, providing a compact, motionless solution that enables monolithic integration with high reliability and a long operational lifetime. The flow switching within the system is provided by a unique arrangement of multiple Knudsen pumps that eliminates the need for valves. To realize monolithic integration, the preconcentrator, separation column, and detector are arranged in a planar layout and are designed to be microfabricated using a comm

SUBMITTER: Zhao X 

PROVIDER: S-EPMC12686500 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature