Human members of the eukaryotic protein kinase family.

ABSTRACT:

Background

Eukaryotic protein kinases (EPKs) constitute one of the largest recognized protein families represented in the human genome. EPKs, which are similar to each other in sequence, structure and biochemical properties, are important players in virtually every signaling pathway involved in normal development and disease. Near completion of projects to sequence the human genome and transcriptome provide an opportunity to identify and perform sequence analysis on a nearly complete set of human EPKs.

Results

Publicly available genetic sequence data were searched for human sequences that potentially represent EPK family members. After removal of duplicates, splice variants and pseudogenes, this search yielded 510 sequences with recognizable similarity to the EPK family. Pro

SUBMITTER: Kostich M 

PROVIDER: S-EPMC126868 | biostudies-literature | 2002 Aug

REPOSITORIES: biostudies-literature