Phenolic Compounds of <i>Justicia gendarussa</i> Show Pharmacological Potentials Against Pain, Oxidation, Hyperglycemia, Diarrhea, and Microbes: Phytopharmacological and Computational Approaches.

ABSTRACT:

Background

Justicia gendarussa is a branched shrub spread across Indian, Sri Lankan, and Malaysian forests. It has been widely used across many countries to treat asthma, rheumatism, colics in children, eczema, and HIV. The study goal was to investigate the phytoconstituents from J. gendarussa and to discover its therapeutic potential against various disease conditions.

Methods

The plant sample was collected, dried, and grinded into coarse powder which was then soaked in methanol for 2 weeks. After the maceration process, the crude methanolic extract was subjected to solvent-solvent partitioning into four different fractions: n-hexane soluble fraction (HSF), dichloromethane soluble fraction (DMSF), ethyl acetate soluble fraction (EASF), and aqueous fraction (AQ

SUBMITTER: Munny FA 

PROVIDER: S-EPMC12686832 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature