Cost-Effectiveness of Cryopreserved vs Liquid-Stored Platelets for Managing Surgical Bleeding.

ABSTRACT:

Importance

Platelet transfusion is critical in managing major bleeding, but access to liquid-stored platelets is limited by their 5- to 7-day shelf life. Cryopreserved platelets last up to 2 years and may improve availability, although their cost-effectiveness remains uncertain.

Objective

To evaluate the cost-effectiveness of cryopreserved platelets vs liquid-stored platelets for managing surgical bleeding.

Design, setting, and participants

An economic evaluation was conducted from the Australian government funder perspective alongside the CLIP-II randomized clinical trial, following intention-to-treat principles. Adult patients (age ≥18 years) undergoing cardiac surgery at 11 Australian tertiary hospitals between August 2021 and April 2024 were screened for eligibili

SUBMITTER: Orman Z 

PROVIDER: S-EPMC12687093 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature