Efficacy of pharmacological and non-pharmacological interventions for the treatment of anorexia nervosa in adolescents and adults (EfaNosa): protocol for a network meta-analysis.

ABSTRACT:

Background

Anorexia nervosa (AN) is a severe eating disorder. With a lifetime prevalence of 1.4% in women and 0.2% in men, an increasing incidence and the highest mortality rate of all mental disorders, it is recognized as a major public health threat. Although the number of available treatments is increasing worldwide, the comparative efficacy and safety of different treatment options have not been investigated systematically. In this systematic review with network meta-analysis (NMA), we aim to assess the efficacy and safety of pharmacological and non-pharmacological interventions in adolescents and adults with AN.

Methods

We will consider randomized controlled trials investigating pharmacological (e.g., antidepressants) and non-pharmacological (e.g., cognitive behavioral

SUBMITTER: Halter F 

PROVIDER: S-EPMC12687480 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature