Temporal trends in the burden of heart failure in childbearing females aged 15-49 years globally from 1990 to 2021 and predictions for 2021-2050.

ABSTRACT:

Background

Heart failure in childbearing females aged 15-49 years has shown a steady global increase, with prevalence rising from 1.74 million cases in 1990 to 3.09 million cases in 2021, largely driven by metabolic dysfunction, pregnancy-related complications, and demographic shifts. This study evaluates temporal trends and projections of heart failure burden in this population using data from the Global Burden of Disease (GBD) Study 2021.

Methods

Data on heart failure prevalence, years lived with disability (YLDs), and age-standardized rates (ASRs) were extracted from GBD 2021 for females aged 15-49 years. Linear regression analysis assessed temporal trends (1990-2021), while Bayesian age-period-cohort, autoregressive integrated moving average, and exponential smoothing mo

SUBMITTER: Lin Y 

PROVIDER: S-EPMC12687501 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature