Self-Coacervation of Oligo(ethylene glycol) and Oligo(2-ethyl-2-oxazoline)-Based Double Hydrophilic Brush Block Copolymers in Aqueous Solution.

ABSTRACT: Coacervates are a highly relevant class of structures formed via liquid-liquid phase separation and new coacervate-forming polymers are highly sought after. Here, the formation of simple coacervate droplets from a double hydrophilic block copolymer (DHBC) with the combination of poly(oligo ethylene glycol methacrylate) (POEGMA) and poly(oligo 2-ethyl-2-oxazoline methacrylate) (POEtOx) without the use of external triggers or charges is shown. At a high concentration of 25 wt.%, the DHBC forms coacervate droplets with sizes in the low micrometre range. The droplets have relatively high stability over a long period of time with only minor coalescence observed after 4 weeks. At low concentrations, no coacervation is observed. Furthermore, copolymers of the monomers also do not show coacervatio

SUBMITTER: Bayliss N 

PROVIDER: S-EPMC12687681 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature