Mortality and Neurodevelopmental Outcome in an Italian Cohort of Very Low Birth Weight Infants.

ABSTRACT:

Aim

Preterm infants face high risks of mortality and neurodevelopmental impairment. We aimed to evaluate the outcomes in an Italian cohort of very low birth weight infants.

Methods

This multicenter prospective study included very low birth weight infants born in Italy between 2016 and 2020. Severe functional disability was defined as cognitive impairment, cerebral palsy, blindness or deafness.

Results

A total of 1381 patients were enrolled (median gestational age: 29.1 weeks; males: 678) and 136 (9.8%) died. Multivariate analysis identified gestational age (OR 0.65), prenatal steroids (OR 0.36), magnesium sulphate (OR 0.48), advanced resuscitation (OR 4.04) and admission body temperature (OR 0.84) as predictors of mortality. A total of 802 (65.5%) completed the 24-mon

SUBMITTER: Lugli L 

PROVIDER: S-EPMC12687702 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature