Circular RNAs in diabetes mellitus and its complications: a systematic review and in silico analyses.

ABSTRACT:

Introduction

Circular RNAs (circRNAs) have garnered attention as potential biomarkers for diabetes mellitus (DM) and its complications due to their stability and presence in various tissues and plasma. The objective of this study was to perform a systematic review of the available literature to better understand the involvement of circRNAs in DM and its chronic complications.

Methods

PubMed and Embase repositories were searched to identify all studies that evaluated the expression of one or more circRNAs in samples from individuals with DM and without DM. Studies comparing circRNA expression between DM patients with or without chronic complications were also included.

Results

In total, 2990 articles were found in the databases and, after excluding articles that did no

SUBMITTER: Dieter C 

PROVIDER: S-EPMC12687764 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature