Complete reconstruction of the crystalline lens shape from OCT images acquired with off-axis viewing.

ABSTRACT: The crystalline lens of the eye is an optical structure that, together with the cornea, focuses images onto the retina. In a young and healthy eye, the lens is transparent and adjust its shape to focus on near and distant objects (accommodation). With age, it loses this flexibility (presbyopia) and may later become opaque (cataract). Understanding the full three-dimensional geometry of the crystalline lens is essential for studying age-related lens growth and accommodation mechanisms, as well as for the selection and design of customized intraocular lenses for implantation in cataract surgery. While Optical Coherence Tomography (OCT) allows imaging of the central lens region visible through the pupil, conventional in vivo measurements cannot capture the full lens shape, particularly at the

SUBMITTER: de la Pena A 

PROVIDER: S-EPMC12687823 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature