Predictive value of motor-evoked potentials for upper limb functional outcomes in acute ischemic stroke.

ABSTRACT:

Background

Stroke remains a leading cause of acquired physical disability globally, with upper limb motor impairment significantly affecting independence and quality of life. Currently, objective neurophysiological biomarkers are not routinely incorporated into stroke care. This study aimed to investigate the predictive value of MEPs for upper limb outcomes in acute ischemic stroke.

Patients and methods

This prospective cohort study included 133 adults experiencing their first acute ischemic stroke. Within 10 days of onset, participants underwent Motor-evoked potential (MEP) testing via transcranial magnetic stimulation (TMS) and were categorized as MEP+ (with preserved responses) or MEP- (with absent responses). Outcome measures included the Fugl-Meyer Assessment (FMA), Bar

SUBMITTER: Yen CC 

PROVIDER: S-EPMC12687903 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature