Diabetes-specific oral nutritional supplement for prediabetes improves postprandial glycemic responses: an open-label, crossover clinical trial.

ABSTRACT:

Background/objectives

Regulating the postprandial glucose levels is crucial for preventing the progression of prediabetes to diabetes. This study examined the effects of a diabetes-specific nutrition formula (DSNF) on the postprandial plasma glucose, serum insulin, and serum c-peptide levels in individuals with prediabetes.

Subjects/methods

An open-label, crossover clinical trial was conducted to compare the effects of the DSNF versus standard oral nutritional supplement (ONS) on glycemic control. Fifteen subjects with prediabetes were enrolled and received the DSNF on the first visit and standard ONS on the second. The postprandial plasma glucose, serum insulin, and serum c-peptide incremental area under the curve (iAUC), as well as the incremental maximal concentration (iC

SUBMITTER: Hwang Y 

PROVIDER: S-EPMC12687991 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature