Atlantal facet geometry in Chiari I malformation.

ABSTRACT:

Introduction

Chiari I malformation (CMI) is a complex condition characterized by cerebellar herniation through the foramen magnum and is frequently coincident with other craniovertebral junction abnormalities. Symptoms are varied, and the complete disease etiology is poorly understood. The primary aim of our study is to assess atlantal facet geometry in CMI patients to further elucidate disease pathogenesis.

Materials and methods

Forty-six CMI-affected female patients (29.48 years ± 8.35) (Chiari1000 database) and 55 female controls (32.11 years ± 4.81) (New Mexico Decedent Image Database [NMDID]) were included. Twenty 3D landmarks were placed around the perimeter of each facet by a blinded landmarker. Coordinates were subjected to a generalized Procrustes superimposition. A

SUBMITTER: Millard JA 

PROVIDER: S-EPMC12688293 | biostudies-literature | 2025 Oct-Dec

REPOSITORIES: biostudies-literature