Preeclampsia and the Long-Term Risk of Developing Neurological Disorders Requiring Hospital Admission.

ABSTRACT:

Introduction

Preeclampsia is associated with acute neurological complications during pregnancy, but the subsequent risk of developing a neurological disorder is unclear. We determined if preeclampsia was associated with the long-term risk of neurological morbidity.

Methods

We conducted a longitudinal cohort study of 1,460,098 pregnant women with and without preeclampsia in QC, Canada, between 1989 and 2023. The main exposure measure was preeclampsia diagnosed in any pregnancy. Outcomes included hospitalization for cerebrovascular disease, epilepsy, and other neurological disorders up to 3 decades after pregnancy. Using Cox regression models adjusted for confounders, we estimated hazard ratios (HR) and 95% confidence intervals (CI) for the association between preeclampsia and

SUBMITTER: Auger N 

PROVIDER: S-EPMC12688377 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature