Nationwide Analysis of Spontaneous Coronary Artery Dissection-Related Acute Myocardial Infarction in Japanese Patients Aged ≤60 Years Using the Administrative JROAD-DPC Database.

ABSTRACT:

Background

Spontaneous coronary artery dissection (SCAD) causes acute myocardial infarction (AMI). Clinical characteristics of SCAD patients remain insufficiently understood.

Methods and results

We analyzed AMI patients aged ≤60 years using the nationwide Japanese Registry of All Cardiac and Vascular Diseases-Diagnosis Procedure Combination database (2012.04.01-2022.03.31). SCAD was defined by International Classification of Diseases, 10th revision code I24.8 and the presence of keyword 'coronary artery dissection'. The primary outcome was in-hospital all-cause mortality. Among 96,304 eligible patients, 330 (0.34%) had SCAD. SCAD patients were younger (P<0.001), more often female (P<0.001), and had fewer atherogenic risk factors. They less frequently received aspirin (P<0.00

SUBMITTER: Wayama K 

PROVIDER: S-EPMC12688434 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature