Interleukin-6-to-lymphocyte count ratio in the prognosis of moderate-to-severe acute respiratory distress syndrome supported by venovenous extracorporeal membrane oxygenation: a single-center retrospective study.

ABSTRACT:

Background

Inflammation and immune status are essential in acute respiratory distress syndrome (ARDS), wherein excessive inflammation with severe immunosuppression is associated with a poor prognosis. This study investigated the interleukin-6 (IL-6) and lymphocyte count (Lym) in patients with moderate-to-severe ARDS supported by venovenous extracorporeal membrane oxygenation (VV ECMO), as well as their relationship with prognosis, providing new insights for clinical prognosis evaluation.

Methods

A single-center, retrospective cohort study was conducted using data collected between March 2022 and July 2024. A total of 117 patients with moderate-severe ARDS with VV ECMO support were enrolled in this study. The observational clinical outcome was intensive care unit (ICU) 28-day

SUBMITTER: Tan X 

PROVIDER: S-EPMC12688499 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature