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Association between stress hyperglycemia ratio and 28-day all-cause mortality in critically ill atrial fibrillation patients: a retrospective cohort study based on the MIMIC-IV database.


ABSTRACT:

Background

Atrial fibrillation (AF) is a prevalent arrhythmia linked to high mortality rates. The stress hyperglycemia ratio (SHR) serves as a novel marker for acute metabolic stress; however, its significance in critically ill patients with AF is not yet fully understood. This study seeks to investigate the correlation between SHR and 28-day all-cause mortality among critically ill patients diagnosed with AF.

Methods

This study utilized the Intensive Care Medicine Information Market (MIMIC-IV v2.2) database to identify and enroll 2,050 adult patients admitted to intensive care units (ICU) with AF. The SHR was calculated using the formula: SHR = inpatient blood glucose (mg/dL) / [28.7 × glycosylated hemoglobin (HbA1c) (%) - 46.7]. Patients were then divided into four groups

SUBMITTER: Zhang Q 

PROVIDER: S-EPMC12688549 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature