Risk factors and survival associated with lung cancer recurrence after curative-intent surgery: beyond TNM pathological staging.

ABSTRACT:

Background

Lung cancer recurrence following curative-intent surgery remains a challenge for multi-disciplinary care teams. Currently, tumor, node, metastasis (TNM) staging is the main determinant of long-term outcomes and candidacy for perioperative therapies. The purpose of this study was to identify risk factors beyond TNM staging associated with lung cancer recurrence as well as overall survival following recurrence.

Methods

A retrospective institutional database, designed for this cohort study, identified patients who underwent surgery for non-small cell lung cancer (NSCLC) and were found to be disease free in postoperative follow-up from 2004-2014. Patient characteristics, diagnostics, and operations were compared by recurrence of disease using chi squared and analysis

SUBMITTER: Hendriksen BS 

PROVIDER: S-EPMC12688566 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature