Evaluating the role of American Thoracic Society/European Respiratory Society/Japanese Respiratory Society/Latin American Thoracic Society high-resolution CT-thorax usual interstitial pneumonitis imaging categories in selecting candidates for transbronchial lung cryobiopsy for undifferentiated interstitial lung disease, a retrospective study.

ABSTRACT:

Background

The utility of high-resolution computed tomography-thorax (HRCT) in predicting which subtypes of interstitial lung disease (ILD) require tissue diagnosis with transbronchial lung cryobiopsy (TBLC) is unclear. We aim to see if usual interstitial pneumonia (UIP) imaging categories can inform patient selection for TBLC in undifferentiated ILD.

Methods

Retrospective study of 76 patients who underwent TBLC for undifferentiated diffuse ILD at a university hospital between 2017 and 2023. HRCT imaging was reviewed on each patient and categorised as per their American Thoracic Society (ATS)/European Respiratory Society (ERS)/Japanese Respiratory Society (JRS)/Latin American Thoracic Society (ALAT) UIP imaging pattern (definite UIP, probable UIP, indeterminate UIP or altern

SUBMITTER: Landers S 

PROVIDER: S-EPMC12688573 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature