Association between underdiagnosed and overdiagnosed chronic obstructive pulmonary disease with all-cause mortality.

ABSTRACT:

Background

Chronic obstructive pulmonary disease (COPD) underdiagnosis and overdiagnosis are common in clinical practice, but studies on their long-term prognosis remain limited. The study aimed to explore the all-cause mortality of underdiagnosed and overdiagnosed COPD in the general population.

Methods

This retrospective study analyzed participants from the National Health and Nutrition Examination Survey (NHANES) 1988-1994 and 2007-2012 with quality-controlled demographic data, acceptable prebronchodilator spirometry, and all-cause mortality follow-up data. Airflow limitation was defined as forced expiratory volume in 1 second (FEV₁)/forced vital capacity (FVC) < lower limit of normal (LLN), and previously diagnosed COPD as physician-confirmed chronic bronchiti

SUBMITTER: Huang S 

PROVIDER: S-EPMC12688577 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature