Preoperative C-reactive protein-augmented CONUT score as a better prognostic indicator than CONUT alone in non-small cell lung cancer across age groups.

ABSTRACT:

Background

Preoperative nutritional status correlates with outcomes in malignancies. We previously identified the Controlling Nutritional Status (CONUT) score as a sensitive prognostic indicator in elderly non-small cell lung cancer (NSCLC) patients and proposed the C-reactive protein (CRP)-augmented combined CRP and CONUT (C-CONUT) score. The aim of this study was to evaluate whether the C-CONUT score is a more effective prognostic tool than the CONUT score in younger NSCLC patients across different age groups.

Methods

In a retrospective single-center cohort from January 2012 to December 2022 (n=738), we evaluated CONUT and C-CONUT scores in NSCLC patients across three age cohorts (≤79, ≤75, and ≤65 years). Patients receiving neoadjuvant therapy, with stage 0/IIIB disease,

SUBMITTER: Sakai T 

PROVIDER: S-EPMC12688583 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature