Pressure record analysis method parameters during weaning success and failure from mechanical ventilation in prolonged ventilated patients after cardiac surgery.

ABSTRACT:

Background

Pressure recording analytical method (PRAM) parameters, derived from arterial pressure waveform analysis, provide continuous and minimally invasive assessment of cardiovascular function. This study examines the changes in PRAM parameters during the spontaneous breathing trial (SBT) in patients undergoing prolonged mechanical ventilation (PMV, defined as >24 hours) after cardiac surgery and explores their potential to predict the outcomes of SBT.

Methods

In this prospective observational study, 58 adult patients requiring PMV (>24 h) after cardiac surgery underwent a single 60-min SBT. PRAM variables and systemic hemodynamics were recorded immediately before and throughout the trial.

Results

Fifteen patients (25.9%) failed weaning. Generalised estimating equ

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC12688627 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature