Global and regional burden of gout in middle-aged adults, 1990-2021, with projections to 2046: An observational study analysis for GBD 2021.

ABSTRACT: The prevalence of gout among middle-aged populations are rising notably. However, there is a lack of comprehensive data on their global burden and epidemiological trends. This study aimed to examine the global trend of gout in middle-aged populations from the Global Burden of Disease (GBD) 2021 database. Using GBD 2021, this study evaluated trends of incidence, prevalence, years lived with disability (YLDs) of gout in middle-aged populations. Multidimensional stratification analyzed temporal patterns, sex patterns, geographic variations, and Socio-demographic Index (SDI). Comprehensive methods included Estimated Annual Percentage Change, Joinpoint regression, decomposition analysis, and Nordpred predictive modeling. From 1990 to 2021, the global burden of gout in middle-aged populations in

SUBMITTER: Ren Y 

PROVIDER: S-EPMC12688835 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature