Hemoglobin glycation index and mortality in chronic heart failure: A retrospective cohort study.

ABSTRACT: This study investigates the association between the hemoglobin glycation index (HGI) and 90-day and 365-day all-cause mortality (ACM) in hospitalized patients with chronic heart failure (CHF). A total of included 2964 hospitalized CHF patients from the Medical Information Mart for Intensive Care IV database were included. HGI was calculated as observed glycated hemoglobin (HbA1c) minus the cohort-specific predicted HbA1c estimated from a linear regression of HbA1c on fasting plasma glucose. We ascertained 90-day and 365-day ACM from database-recorded dates of death, counting events during the index hospitalization and after discharge within each window. Cox proportional hazards regression models were used to examine the association of HGI with 90-day and 365-day ACM. Restricted cubic splin

SUBMITTER: Lyu C 

PROVIDER: S-EPMC12688929 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature