Adipokines and adiposity indices as predictors of glycemic status, insulin resistance, and metabolic dysfunction-associated steatotic liver disease in apparently healthy adults.

ABSTRACT: Abnormal serum adipokines such as Leptin and Adipokines, are linked to metabolic diseases, insulin resistance, and fatty liver. Obesity indices like body mass index, waist-to-height ratio, waist-to-hip ratio, and fat percentage are also associated but with debate accuracy. Fat distribution, measured with visceral (VAT) and subcutaneous adipose tissue (SAT) via ultrasound, may provide more precise assessment. However, no study has yet evaluated all these parameters together. This study aims to assess the association of serum adiponectin, leptin, obesity indeces, and fat distribution with glycemic status, insulin resistance, and fatty liver and to identify the strongest independent predictors among these factors in apparently healthy adults. In an observational cross-sectional study, sixty-f

SUBMITTER: Mahmood T 

PROVIDER: S-EPMC12688955 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature