Efficacy of Topical Manuka Honey for Chronic Rhinosinusitis After Endoscopic Sinus Surgery: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background and objectives

The aim of this study was to perform a systematic review and meta-analysis evaluating the efficacy of topical manuka honey in the postoperative management of chronic rhinosinusitis following endoscopic sinus surgery.

Methods

A systematic search was conducted using PubMed, Embase, OVID, Google Scholar, Web of Science, and the Cochrane Central Register of Controlled Trials. Data were extracted from the randomized trials identified for meta-analysis. Outcome measures-including visual analogue scales, quality of life assessed by the Sinonasal Outcome Test-22, the Philpott-Javer endoscopic score or Lund-Kennedy endoscopic score, post-treatment culture negativity, and adverse effects-were compared between the manuka honey treatment and control groups. Het

SUBMITTER: Kang YJ 

PROVIDER: S-EPMC12689086 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature