Association between geriatric nutritional risk index and fecal incontinence in individuals with stroke: mediating roles of systemic immune inflammation index and oxidative balance scores.

ABSTRACT:

Background

This study aims to investigate the association of geriatric nutritional risk index (GNRI) with fecal incontinence (FI) and fecal incontinence severity index (FISI) in individuals with stroke and to explore potential mechanisms underlying this link.

Methods

Data were from the health examination centers of Lishui Municipal Center Hospital and Shanghai Deji Hospital, with 1906 participants. Multivariate logistic regression models, multivariate linear regression models, and restricted cubic spline (RCS) models were applied to assess the association of GNRI with FI and FISI in individuals with stroke. Subgroup analyses and interaction tests were performed to evaluate heterogeneity. Sensitivity analyses were used to test the robustness of the findings. Mediation analysi

SUBMITTER: Xiang Y 

PROVIDER: S-EPMC12689289 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature