Myosteatosis as an independent predictor for all-cause and cardiac mortality in initial-dialysis patients: a multicenter, retrospective cohort study.

ABSTRACT:

Background

Myosteatosis is associated with adverse prognosis in diseases. We aimed to establish thresholds for myosteatosis, assess its association with all-cause and cardiac mortality in initial dialysis patients, and construct a myosteatosis-based survival nomogram. assessed the predictive value of myosteatosis with all-cause and cardiac mortality in initial-dialysis patients, and constructed a myosteatosis-based survival nomogram.

Methods

This multicentric retrospective study included 383 initial-dialysis patients (1/2014-12/2019). Endpoints include all-cause and cardiac mortality. Skeletal Muscle Index (SMI, cm²/m²) and Skeletal Muscle Density (SMD, Hounsfield Units [HU]) were measured at the third lumbar vertebra (L3) level by computed tomography (

SUBMITTER: Hou SM 

PROVIDER: S-EPMC12689326 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature