Personalized prevention of neurodegenerative diseases: scoping review and evidence gap map.

ABSTRACT: Neurodegenerative diseases represent a major public health challenge due to their high prevalence and poor prognosis. Identifying biomarkers to stratify individuals by their risk of developing these diseases may help to define new personalized prevention interventions. The objective of this study was to conduct a scoping review of biomarkers for primary and secondary personalized prevention of neurodegenerative diseases. The search targeted biomarkers in adults or high-risk subpopulations in clinical or public health settings for Alzheimer's disease, vascular dementia, Lewy body disease, frontotemporal dementia, Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis. Ultimately, 286 papers were included in the review and the interactive gap map. There is a strong focus

SUBMITTER: Barahona-Lopez C 

PROVIDER: S-EPMC12689453 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature