Healthy dietary patterns for prevention of neuropsychiatric disorders: role of inflammatory and metabolic mechanisms.

ABSTRACT: Diet is increasingly being recognized as a modifiable lifestyle factor that plays an important role in neuropsychiatric health. However, existing research has focused on single foods or dietary patterns in relation to specific diseases, limiting their ability to inform precise dietary recommendations. Based on UK Biobank data, we applied Cox regression to assess associations between four healthy dietary patterns and risks of dementia, depression, and anxiety. Moreover, we utilized structural equation modeling to explore potential biological pathways. Our results indicated that Alternate Mediterranean Diet (AMED) demonstrated the strongest protective effect against all-cause dementia (0.92 (0.85-0.99)). Regarding depression, the AMED (0.93 (0.89-0.98)) and Alternative Healthy Eating Index-2

SUBMITTER: Xu Y 

PROVIDER: S-EPMC12689847 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature