Genome-wide identification and expression profiling of bHLH transcription factors associated with ferulic acid biosynthesis in <i>Angelica sinensis</i>.

ABSTRACT: This study identifies 148 bHLH transcription factors in Angelica sinensis and reveals four putative candidates associated with ferulic acid biosynthesis, providing a genetic foundation for metabolic engineering to enhance the plant's medicinal value. The basic helix-loop-helix (bHLH) proteins regulate plant growth, development, stress responses, and secondary metabolites. While well-characterized in woody plants, they remain unexplored in Angelica sinensis (A. sinensis), a medicinal plant renowned for bioactive compounds including ferulic acid. Therefore, we systematically identified and characterized bHLH transcription factors in A. sinensis through whole-genome analysis and transcriptome profiling, identifying putative genes potentially regulatin

SUBMITTER: Arshad KT 

PROVIDER: S-EPMC12689882 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature