Transcriptome and metabolome analyses revealed the main profiles contributing the mild aroma characteristics of <i>Artemisia stolonifera</i>.

ABSTRACT: Artemisia stolonifera, identified as an original source of mugwort leaf during the fourth national medicinal resource investigation in China, remains considerably understudied compared to the well-characterized Artemisia argyi, despite its distinctive mild aroma and potential therapeutic value. The lack of systematic comparative analyses on their active compounds and underlying biosynthetic mechanisms has limited the application and development of A. stolonifera. To address this gap, we conducted integrated metabolomic and transcriptomic analyses of leaves from both species. Using GC-MS for targeted profiling of volatile organic compounds and UPLC-ESI (-Q TRA)-MS/MS for flavonoids and lignin pathway intermediates, we identified 1,728 differentially accumulated metaboli

SUBMITTER: Cao Y 

PROVIDER: S-EPMC12689896 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature