Whole genome sequencing as a reliable alternative for <i>Salmonella</i> serotyping: a comparative study with the gold-standard method.

ABSTRACT:

Introduction

Salmonella is a major foodborne pathogen of significant global health concern, leading to conditions like gastroenteritis, with symptoms such as diarrhea, abdominal cramps, and fever. Although most cases are self-limiting, Salmonella enterica can cause bacteremia or typhoid fever in some cases. There are over 2600 known serotypes of S. enterica. Each serotype is distinguished by differences in its surface antigens (somatic O and flagellar H), which is the basis for their classification. Considering that traditional phenotypic typing is laborious and time-consuming, the goal of this study is to evaluate whole genome sequencing for S. enterica classification.

Methods

From January 2021 to December 2024, 282 isolates of S. enterica

SUBMITTER: Mileto I 

PROVIDER: S-EPMC12689982 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature