Synthetic hydroxyapatite: a perfect substitute for dental enamel in biofilm formation studies.

ABSTRACT: In contact with saliva, tooth enamel is covered by biomolecules forming an initial biofilm. Microorganisms attach to the initial biofilm and form the bacterial biofilm, which can provoke diseases. Therefore, dental biofilms are the focus of preventive research. Enamel consists mainly of hydroxyapatite (HAP). Yet, the composition of dental apatite differs between individuals and influences enamel properties. Standardized surfaces might therefore be useful for biofilm research. Synthetic enamel-like HAP pellets perfectly meet the criteria for such well-defined samples. However, systematic investigations of synthetic HAP on oral biofilm formation have never been performed, especially not in comparison to enamel. Therefore, we systematically compared the in situ biofilm formation on synthetic

SUBMITTER: Dudek J 

PROVIDER: S-EPMC12690089 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature