In Planta Application and Efficacy of FireFighter-A Phage Cocktail for Combating Fire Blight.

ABSTRACT: Fire blight, caused by Erwinia amylovora, poses a significant threat to Rosaceae crops and has caused substantial damage to South Korea since its emergence in 2015. Traditional control methods, including antibiotic- and copper-based treatments, have shown limitations, underscoring the necessity for alternative solutions to enhance efficacy while addressing the concerns associated with antibiotics. This study evaluated the efficacy of FireFighter-A, a novel phage cocktail, in managing fire blight. Comprising four phages-Fifi318, Fifi451, pEa_27, and pEa_47-FireFighter-A demonstrates a broad host range that covers all recent isolates against E. amylovora and E. pyrifoliae, along with high stability under various conditions, including temperature, pH, and buffers. Trials with immature apple f

SUBMITTER: Kim SG 

PROVIDER: S-EPMC12690260 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature