Effect of Dual-Task Training on Cognitive Function in Community-Dwelling Older Adults With Mild Cognitive Impairment: Sequential Multiple Assignment Randomized Trial.

ABSTRACT:

Background

Nonpharmacological interventions are important prevention strategies for mild cognitive impairment (MCI), but effects vary significantly between individuals based on personal characteristics, while current practice relies on experience-based approaches lacking personalized, adaptive intervention strategies.

Objective

The objective of our study was to develop and evaluate evidence-based adaptive intervention strategies for optimizing cognitive function among older adults with MCI using a Sequential Multiple Assignment Randomized Trial (SMART) design, comparing the effectiveness of cognitive training (CT) combined with virtual reality Taichi (VRTC) versus offline Taichi (OffTC) versus control, and to identify baseline characteristics that predict treatment response

SUBMITTER: Yu C 

PROVIDER: S-EPMC12690282 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature