Impact of donor-recipient sex-matching patterns on liver transplantation outcomes: a cohort study based on United Network of Organ Sharing data.

ABSTRACT:

Background

The impact of donor-recipient sex-matching patterns on the outcomes of liver transplantation (LT) remains controversial. We aim to compare the long-term graft and recipient survival of LT among four donor-recipient sex-matching patterns using United Network of Organ Sharing (UNOS) database, and develop a grading system for prognostic stratification.

Methods

Adult primary LT recipients from February, 2002 to June, 2022 in the UNOS database were divided into four donor-recipient sex groups, including female donor-female recipient (F-F) group, female donor-male recipient (F-M) group, male donor-female recipient (M-F) group and male donor-male recipient (M-M) group. Propensity score matching (PSM) analysis, inverse probability treatment weighting and multivariable adj

SUBMITTER: Gao F 

PROVIDER: S-EPMC12690319 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature