Systemic Effects of Pesticides on Insectivorous Bats: A Proteomics Approach.

ABSTRACT: Bats play a critical role controlling agricultural pests, yet foraging in croplands exposes them to hazardous pesticides. These chemicals pose significant risks for bats by impairing immune function, locomotion, and cognition even at low doses, jeopardizing their survival and ecological role. Here, we employed proteomics-a powerful, yet underused, tool in ecotoxicology-to examine the systemic effects of chlorpyrifos (CPF), a commonly used insecticide, on big brown bats (Eptesicus fuscus). We exposed bats through their diet to an environmentally relevant concentration of CPF for three or seven consecutive days and took plasma samples before and after exposure for non-targeted proteomics. We identified over 100 proteins with significant abundance changes before and after exposure to the pest

SUBMITTER: Sandoval-Herrera N 

PROVIDER: S-EPMC12690467 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature